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1.64M
impressions
221M
likes
760K
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35.7K
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"Every male 40 and older should probably be taking somewhere between 2.5 and 5 milligrams of tadalafil." - @hubermanlab Jordi: What do you think the best athletes in the world are doing this Olympics? Huberman: "People are taking vasodilators. You know, Viagra and tadalafil, which commonly goes by Cialis." "Tadalafil is a vasodilator. It lowers blood pressure, and people know of it as Cialis for erectile dysfunction. It was originally developed as a drug to improve prostate health." "The basic takeaway is that most every male 40 and older should probably be taking somewhere between 2.5 and 5 milligrams of tadalafil—not necessarily for erectile function, although it will augment that as well—but to lower blood pressure and to improve vasodilation for the brain and the prostate." "And I'm not saying this as a biohacker or a podcaster. Our head of male sexual health from Stanford, Mike Eisenberg, MD, PhD. He is best in class in terms of male sexual health endocrinology. That's his recommendation."
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"Every male 40 and older should probably be taking somewhere between 2.5 and 5 milligrams of tadalafil." - @hubermanlab Jordi: What do you think the best athletes in the world are doing this Olympics? Huberman: "People are taking vasodilators. You know, Viagra and tadalafil, which commonly goes by Cialis." "Tadalafil is a vasodilator. It lowers blood pressure, and people know of it as Cialis for erectile dysfunction. It was originally developed as a drug to improve prostate health." "The basic takeaway is that most every male 40 and older should probably be taking somewhere between 2.5 and 5 milligrams of tadalafil—not necessarily for erectile function, although it will augment that as well—but to lower blood pressure and to improve vasodilation for the brain and the prostate." "And I'm not saying this as a biohacker or a podcaster. Our head of male sexual health from Stanford, Mike Eisenberg, MD, PhD. He is best in class in terms of male sexual health endocrinology. That's his recommendation."
When we sat down with @alexandr_wang at Meta Connect 2025, he shared his advice for young people: “If you’re 13 right now, you should spend all your time vibe coding. This is the Bill Gates, Mark Zuckerberg moment. The people who grow up with these tools will have an immense advantage in the future economy.” From his appearance on the show in September.
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When we sat down with @alexandr_wang at Meta Connect 2025, he shared his advice for young people: “If you’re 13 right now, you should spend all your time vibe coding. This is the Bill Gates, Mark Zuckerberg moment. The people who grow up with these tools will have an immense advantage in the future economy.” From his appearance on the show in September.
Netflix rejected a $12M offer from Bezos in 1999. Blockbuster "laughed [Netflix] out of the room" when Netflix offered to sell to them for $50M. Today they announced their acquisition of Warner Bros, and have a market cap of $426B.
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Netflix rejected a $12M offer from Bezos in 1999. Blockbuster "laughed [Netflix] out of the room" when Netflix offered to sell to them for $50M. Today they announced their acquisition of Warner Bros, and have a market cap of $426B.
Here is the full letter Leopold sent to his LPs last night. Rumors of his demise are greatly exaggerated.
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Here is the full letter Leopold sent to his LPs last night. Rumors of his demise are greatly exaggerated.
Apple's Eddy Cue reveals the logic behind charging $0.99 a song when the company launched iTunes Store in 2003, despite the fact that Apple would lose money at that price: "There were two keys to $0.99 that we really believed in, and people didn't see." "Number one is when the price is $0.99, and it's consistent, you never have to think about price." "The second thing was that people could never do that, because at $0.99, if you're charging a credit card, you would lose money. Because credit cards have a fixed fee and a percentage that you pay." "Well, the fixed fee and the percentage you pay on a $0.99 song was like a quarter, and the vast majority of the [rest of] the money went to the labels. So every time we'd sell a song, we'd lose money. Nobody wanted to do that." "What we decided to do is, as we were building this — and it was a huge discussion, because we would lose a ton of money — we said, 'Look, this thing is amazing. You're not going to buy just one song, you're going to buy a lot of songs.'" "'And when you do that, instead of closing the transaction on every single one, why don't we just combine them over a period of time? Let's keep the transaction open for a period of time — let's call it 24 hours, or 8 hours. And everything you buy, we're just going to give you, then we're going to charge you at the end.'" "And that's exactly what happened. Very few transactions were just $0.99. Most of the transactions were multiple dollars. And the fixed fee didn't matter."
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Apple's Eddy Cue reveals the logic behind charging $0.99 a song when the company launched iTunes Store in 2003, despite the fact that Apple would lose money at that price: "There were two keys to $0.99 that we really believed in, and people didn't see." "Number one is when the price is $0.99, and it's consistent, you never have to think about price." "The second thing was that people could never do that, because at $0.99, if you're charging a credit card, you would lose money. Because credit cards have a fixed fee and a percentage that you pay." "Well, the fixed fee and the percentage you pay on a $0.99 song was like a quarter, and the vast majority of the [rest of] the money went to the labels. So every time we'd sell a song, we'd lose money. Nobody wanted to do that." "What we decided to do is, as we were building this — and it was a huge discussion, because we would lose a ton of money — we said, 'Look, this thing is amazing. You're not going to buy just one song, you're going to buy a lot of songs.'" "'And when you do that, instead of closing the transaction on every single one, why don't we just combine them over a period of time? Let's keep the transaction open for a period of time — let's call it 24 hours, or 8 hours. And everything you buy, we're just going to give you, then we're going to charge you at the end.'" "And that's exactly what happened. Very few transactions were just $0.99. Most of the transactions were multiple dollars. And the fixed fee didn't matter."
ON THIS DAY: Mark Zuckerberg rebrands Facebook as Meta. “To reflect who we are and the future we hope to build, I’m proud to share that our company is now Meta... For me, it symbolizes that there is always more to build, and there is always a next chapter to the story.”
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ON THIS DAY: Mark Zuckerberg rebrands Facebook as Meta. “To reflect who we are and the future we hope to build, I’m proud to share that our company is now Meta... For me, it symbolizes that there is always more to build, and there is always a next chapter to the story.”
“This is going to be a trillion-dollar drug.” @hubermanlab says retatrutide is the peptide that’s about to “change everything.” Currently in a Phase III clinical trial in humans, retatrutide caused up to one-third body weight loss in just six months, with some degree of muscle sparing. “The bodybuilding community has been onto this for a long time.” “Then it shows up in Hollywood. Everyone lies or avoids answering the question of how they got so jacked. They talk about eating chicken breasts, and they’re actually taking growth hormone, Winstrol, and retatrutide.” “We are looking at a potential change in the laws around peptides such that buying peptides would become illegal. I think this is a terrible idea, but the motivation behind this is largely because Eli Lilly owns the patent.” “Lilly would like to protect the domain over that patent. This is going to be a trillion-dollar drug.”
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“This is going to be a trillion-dollar drug.” @hubermanlab says retatrutide is the peptide that’s about to “change everything.” Currently in a Phase III clinical trial in humans, retatrutide caused up to one-third body weight loss in just six months, with some degree of muscle sparing. “The bodybuilding community has been onto this for a long time.” “Then it shows up in Hollywood. Everyone lies or avoids answering the question of how they got so jacked. They talk about eating chicken breasts, and they’re actually taking growth hormone, Winstrol, and retatrutide.” “We are looking at a potential change in the laws around peptides such that buying peptides would become illegal. I think this is a terrible idea, but the motivation behind this is largely because Eli Lilly owns the patent.” “Lilly would like to protect the domain over that patent. This is going to be a trillion-dollar drug.”
Parents are waking up to how bad screen time is for kids. Schools that have banned phones are seeing extraordinary results. @esaagar breaks down the vibe shift, and says parents are now asking to get rid of school-issued Chromebooks and switch back to pencil and paper.
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Parents are waking up to how bad screen time is for kids. Schools that have banned phones are seeing extraordinary results. @esaagar breaks down the vibe shift, and says parents are now asking to get rid of school-issued Chromebooks and switch back to pencil and paper.
BREAKING: After purchasing https://t.co/52aDd0GCeE for $70M, @kris says he was immediately offered $500M for the domain
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BREAKING: After purchasing https://t.co/52aDd0GCeE for $70M, @kris says he was immediately offered $500M for the domain
Clawdbot creator @steipete describes his mind-blown moment: it responded to a voice memo, even though he hadn't set it up for audio or voice. "I sent it a voice message. But there was no support for voice messages. After 10 seconds, [Moltbot] replied as if nothing happened." "I'm like 'How the F did you do that?'" "It replied, 'You sent me a message, but there was only a link to a file with no file ending. So I looked at the file header, I found out it was Opus, and I used FFmpeg on your Mac to convert it to a .wav. Then I wanted to use Whisper, but you didn't have it installed. I looked around and found the OpenAI key in your environment, so I sent it via curl to OpenAI, got the translation back, and then I responded.'"
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Clawdbot creator @steipete describes his mind-blown moment: it responded to a voice memo, even though he hadn't set it up for audio or voice. "I sent it a voice message. But there was no support for voice messages. After 10 seconds, [Moltbot] replied as if nothing happened." "I'm like 'How the F did you do that?'" "It replied, 'You sent me a message, but there was only a link to a file with no file ending. So I looked at the file header, I found out it was Opus, and I used FFmpeg on your Mac to convert it to a .wav. Then I wanted to use Whisper, but you didn't have it installed. I looked around and found the OpenAI key in your environment, so I sent it via curl to OpenAI, got the translation back, and then I responded.'"

Introducing Claude with Ads Free access to Anthropic’s most powerful model, powered by ads. Try it now: t.co/QU43cgIJRm

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Introducing Claude with Ads Free access to Anthropic’s most powerful model, powered by ads. Try it now: https://t.co/QU43cgIJRm
BREAKING: @bchesky’s 𝕏 account was hacked, posting a since-deleted AI slop thread, per Fortune
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BREAKING: @bchesky’s 𝕏 account was hacked, posting a since-deleted AI slop thread, per Fortune
In an effort to expand awareness of technology and business, we bought a Super Bowl ad. See you Sunday on NBC
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In an effort to expand awareness of technology and business, we bought a Super Bowl ad. See you Sunday on NBC
Sequoia partner @sonyatweetybird says we're going from the age of product-led growth to the age of agent-led growth. "You see this most clearly if you're using Claude Code actively. It says, 'Hey, for a database, you should use Supabase. For hosting, use Vercel.' It's choosing for you, the stuff you should be using." "Product-led growth brought us closer to the vision of 'best product wins,' but ultimately people are still lazy. They can't read all the reviews, and they kind of default to what looks cool on the website." "Whereas your agent has infinite time to go and make these choices for you. It can go and read all the documentation, read all the user comments, and figure out [what you need] for your use case."
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Sequoia partner @sonyatweetybird says we're going from the age of product-led growth to the age of agent-led growth. "You see this most clearly if you're using Claude Code actively. It says, 'Hey, for a database, you should use Supabase. For hosting, use Vercel.' It's choosing for you, the stuff you should be using." "Product-led growth brought us closer to the vision of 'best product wins,' but ultimately people are still lazy. They can't read all the reviews, and they kind of default to what looks cool on the website." "Whereas your agent has infinite time to go and make these choices for you. It can go and read all the documentation, read all the user comments, and figure out [what you need] for your use case."
"You can break AI down into 5 tiers." - George Hotz "Data centers - tier 1, fabs - tier 2, Nvidia/AMD - tier 3, OpenAI/Anthropic - tier 4, and completely worthless things like Cursor and Windsurf, which are tier 5." "OpenAI and Anthropic will eat all the value from the Cursors and Windsurfs of the world. I argue that the tier 4s (OpenAI/Anthropic) aren't even going to have value." From his June 2025 appearance, @realGeorgeHotz really raised eyebrows with this clip when it hit the timeline.
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"You can break AI down into 5 tiers." - George Hotz "Data centers - tier 1, fabs - tier 2, Nvidia/AMD - tier 3, OpenAI/Anthropic - tier 4, and completely worthless things like Cursor and Windsurf, which are tier 5." "OpenAI and Anthropic will eat all the value from the Cursors and Windsurfs of the world. I argue that the tier 4s (OpenAI/Anthropic) aren't even going to have value." From his June 2025 appearance, @realGeorgeHotz really raised eyebrows with this clip when it hit the timeline.
Mark Cuban on the next big job students should focus on: Most companies don’t know how to implement AI, especially small businesses. “Companies don’t understand how to implement AI right now to get a competitive advantage… learn to customize a model, walk into a company, show the benefits. That is every single job that’s going to be available for kids coming out of school.” Don’t just study AI. Make it work inside a business. From our August 2025 interview with @mcuban.
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Mark Cuban on the next big job students should focus on: Most companies don’t know how to implement AI, especially small businesses. “Companies don’t understand how to implement AI right now to get a competitive advantage… learn to customize a model, walk into a company, show the benefits. That is every single job that’s going to be available for kids coming out of school.” Don’t just study AI. Make it work inside a business. From our August 2025 interview with @mcuban.
"Go all the way until it hurts. If you're doing something and it's easy, it's not valuable." - @travisk "If anyone says a strategic thing was easy, I'm like, 'You messed up. You could have gone way further. More competitive advantage. More differentiation. Get it together.'"
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"Go all the way until it hurts. If you're doing something and it's easy, it's not valuable." - @travisk "If anyone says a strategic thing was easy, I'm like, 'You messed up. You could have gone way further. More competitive advantage. More differentiation. Get it together.'"
Bloomberg's @markgurman says that even though Apple partnered with Google Gemini for Siri, they actually run their business on Anthropic. "Apple runs on Anthropic at this point. Anthropic is powering a lot of the stuff Apple's doing internally in terms of product development and a lot of their internal tools." "They have custom versions of Claude running on their own servers internally, too. This Google deal just came together a few months ago. They were not going to use Google. Apple actually was going to rebuild Siri around Claude. But Anthropic was holding them over a barrel. They wanted a ton of money from them, several billion dollars a year, and at a price that doubled on an annual basis for the next three years."
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Bloomberg's @markgurman says that even though Apple partnered with Google Gemini for Siri, they actually run their business on Anthropic. "Apple runs on Anthropic at this point. Anthropic is powering a lot of the stuff Apple's doing internally in terms of product development and a lot of their internal tools." "They have custom versions of Claude running on their own servers internally, too. This Google deal just came together a few months ago. They were not going to use Google. Apple actually was going to rebuild Siri around Claude. But Anthropic was holding them over a barrel. They wanted a ton of money from them, several billion dollars a year, and at a price that doubled on an annual basis for the next three years."
.@bryan_johnson: "I've been able to figure out how to compress everything I've learned into one biomarker." "The marker that's durable over time is resting heart rate before bed. Show me your resting heart rate, I'll see your soul. It's an accounting of your life decisions."
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.@bryan_johnson: "I've been able to figure out how to compress everything I've learned into one biomarker." "The marker that's durable over time is resting heart rate before bed. Show me your resting heart rate, I'll see your soul. It's an accounting of your life decisions."
.@travisk's commute takes 5 minutes on a jet ski going 70 mph on Lake Austin. "Who else do you know is jet skiing to work? Nobody. I'm the guy."
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.@travisk's commute takes 5 minutes on a jet ski going 70 mph on Lake Austin. "Who else do you know is jet skiing to work? Nobody. I'm the guy."

TBPN (@tbpn) X Stats & Analytics

TBPN (@tbpn) has 1.64M X followers with a 0.36% engagement rate over the past 12 months. Across 3.36K posts, TBPN received 760K total likes and 221M impressions, averaging 226 likes per post. This page tracks TBPN's performance metrics, top content, and engagement trends — updated daily. To benchmark @tbpn against other accounts, use Socialpruf's X competitor analysis tool.

TBPN (@tbpn) X Analytics FAQ

How many X (Twitter) followers does TBPN have?+
TBPN (@tbpn) has 1.64M X (Twitter) followers as of October 2026.
What is TBPN's X (Twitter) engagement rate?+
TBPN's X (Twitter) engagement rate is 0.36% over the last 12 months, based on 3.36K posts.
How many likes does TBPN get on X (Twitter)?+
TBPN received 760K total likes across 3.36K posts in the last 12 months, averaging 226 likes per post.
How many X (Twitter) impressions does TBPN get?+
TBPN's X (Twitter) content generated 221M total impressions over the last 12 months.
Can I compare TBPN with other X accounts?+
Yes. Add @tbpn to a competitor set with Socialpruf's X competitor analysis tool and benchmark it side by side with any other public accounts on views, engagement rate and follower growth, with history back to each account's first post.